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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATXN3
All Species:
26.67
Human Site:
S278
Identified Species:
45.13
UniProt:
P54252
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54252
NP_001121168.1
364
41781
S278
T
S
G
T
N
L
T
S
E
E
L
R
K
R
R
Chimpanzee
Pan troglodytes
XP_001146724
368
42242
S278
T
S
G
T
N
L
T
S
E
E
L
R
K
R
R
Rhesus Macaque
Macaca mulatta
XP_001116022
352
40079
S270
T
S
G
T
N
L
T
S
E
E
L
R
K
R
R
Dog
Lupus familis
XP_537352
301
34778
A234
E
D
L
Q
R
A
L
A
L
S
R
Q
E
I
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9CVD2
355
40515
S278
T
S
S
P
D
L
S
S
E
E
L
R
R
R
R
Rat
Rattus norvegicus
O35815
355
40428
S278
T
S
S
T
D
L
S
S
E
E
L
R
K
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507271
358
40934
S285
K
P
S
S
S
L
T
S
E
E
L
R
K
R
R
Chicken
Gallus gallus
Q9W689
363
41590
S290
S
Q
T
D
S
L
S
S
E
D
L
R
R
R
R
Frog
Xenopus laevis
NP_001085659
316
35907
N241
N
T
P
Q
S
S
R
N
R
E
T
E
Q
L
T
Zebra Danio
Brachydanio rerio
NP_957398
266
30028
L199
V
E
D
E
E
A
D
L
R
R
A
I
Q
M
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623341
340
38556
F256
Q
R
A
L
Q
L
S
F
E
E
N
K
R
N
D
Nematode Worm
Caenorhab. elegans
O17850
317
35845
I248
V
S
R
S
S
A
E
I
D
E
E
N
L
R
K
Sea Urchin
Strong. purpuratus
XP_786733
388
42119
N310
T
Q
S
S
A
A
S
N
Q
S
T
P
S
E
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M391
280
30674
S213
K
N
T
S
S
G
S
S
A
R
N
K
R
S
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
88.7
79.1
N.A.
80.2
80.4
N.A.
78
70.5
52.2
50.5
N.A.
N.A.
42.8
31.3
38.4
Protein Similarity:
100
97.8
90.1
80.7
N.A.
85.4
85.7
N.A.
85.1
79.9
64.8
61.8
N.A.
N.A.
59.6
48.6
56.4
P-Site Identity:
100
100
100
0
N.A.
66.6
80
N.A.
66.6
46.6
6.6
0
N.A.
N.A.
20
20
6.6
P-Site Similarity:
100
100
100
20
N.A.
86.6
93.3
N.A.
80
80
33.3
6.6
N.A.
N.A.
40
46.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
29
0
8
8
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
8
15
0
8
0
8
8
0
0
0
0
15
% D
% Glu:
8
8
0
8
8
0
8
0
58
65
8
8
8
8
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
22
0
0
8
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
8
0
8
0
% I
% Lys:
15
0
0
0
0
0
0
0
0
0
0
15
36
0
8
% K
% Leu:
0
0
8
8
0
58
8
8
8
0
50
0
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
8
8
0
0
22
0
0
15
0
0
15
8
0
8
8
% N
% Pro:
0
8
8
8
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
8
15
0
15
8
0
0
0
8
0
0
8
15
0
0
% Q
% Arg:
0
8
8
0
8
0
8
0
15
15
8
50
29
58
50
% R
% Ser:
8
43
29
29
36
8
43
58
0
15
0
0
8
8
8
% S
% Thr:
43
8
15
29
0
0
29
0
0
0
15
0
0
0
8
% T
% Val:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _